321 research outputs found
What's Next in Affective Modeling? Large Language Models
Large Language Models (LLM) have recently been shown to perform well at
various tasks from language understanding, reasoning, storytelling, and
information search to theory of mind. In an extension of this work, we explore
the ability of GPT-4 to solve tasks related to emotion prediction. GPT-4
performs well across multiple emotion tasks; it can distinguish emotion
theories and come up with emotional stories. We show that by prompting GPT-4 to
identify key factors of an emotional experience, it is able to manipulate the
emotional intensity of its own stories. Furthermore, we explore GPT-4's ability
on reverse appraisals by asking it to predict either the goal, belief, or
emotion of a person using the other two. In general, GPT-4 can make the correct
inferences. We suggest that LLMs could play an important role in affective
modeling; however, they will not fully replace works that attempt to model the
mechanisms underlying emotion-related processes
Den kollektive læsnings anarki
Denne artikel analyserer, hvordan kunstnerkollektivet Sort Samvittighed bearbejder og bruger litterære tekster i deres forestilling I et forhold fra 2019. Den beskriver deres metode som grundlæggende prattein (van Eikels) med et fokus på forbindelser, kollaborationer og reaktioner frem for forfatternes eventuelle intentioner. Den argumenterer for, at denne praksis skaber et åbent værk, der etablerer fællesskab (Nancy) mellem kunstnerne, forfatterne og publikum
Fast, accurate and automatic ancient nucleosome and methylation maps with epiPALEOMIX
The first epigenomes from archaic hominins (AH) and ancient anatomically modern humans (AMH) have recently been characterized, based, however, on a limited number of samples. The extent to which ancient genome-wide epigenetic landscapes can be reconstructed thus remains contentious. Here, we present epiPALEOMIX, an open-source and user-friendly pipeline that exploits post-mortem DNA degradation patterns to reconstruct ancient methylomes and nucleosome maps from shotgun and/or capture-enrichment data. Applying epiPALEOMIX to the sequence data underlying 35 ancient genomes including AMH, AH, equids and aurochs, we investigate the temporal, geographical and preservation range of ancient epigenetic signatures. We first assess the quality of inferred ancient epigenetic signatures within well-characterized genomic regions. We find that tissue-specific methylation signatures can be obtained across a wider range of DNA preparation types than previously thought, including when no particular experimental procedures have been used to remove deaminated cytosines prior to sequencing. We identify a large subset of samples for which DNA associated with nucleosomes is protected from post-mortem degradation, and nucleosome positioning patterns can be reconstructed. Finally, we describe parameters and conditions such as DNA damage levels and sequencing depth that limit the preservation of epigenetic signatures in ancient samples. When such conditions are met, we propose that epigenetic profiles of CTCF binding regions can be used to help data authentication. Our work, including epiPALEOMIX, opens for further investigations of ancient epigenomes through time especially aimed at tracking possible epigenetic changes during major evolutionary, environmental, socioeconomic, and cultural shifts
Ergodicity-breaking reveals time optimal decision making in humans
Ergodicity describes an equivalence between the expectation value and the
time average of observables. Applied to human behaviour, ergodic theories of
decision-making reveal how individuals should tolerate risk in different
environments. To optimise wealth over time, agents should adapt their utility
function according to the dynamical setting they face. Linear utility is
optimal for additive dynamics, whereas logarithmic utility is optimal for
multiplicative dynamics. Whether humans approximate time optimal behavior
across different dynamics is unknown. Here we compare the effects of additive
versus multiplicative gamble dynamics on risky choice. We show that utility
functions are modulated by gamble dynamics in ways not explained by prevailing
decision theory. Instead, as predicted by time optimality, risk aversion
increases under multiplicative dynamics, distributing close to the values that
maximise the time average growth of wealth. We suggest that our findings
motivate a need for explicitly grounding theories of decision-making on ergodic
considerations.Comment: 43 pages including supplementary methods & material
Tuning the Brake While Raising the Stake:Network Dynamics during Sequential Decision-Making
When gathering valued goods, risk and reward are often coupled and escalate over time, for instance, during foraging, trading, or gambling. This escalating frame requires agents to continuously balance expectations of reward against those of risk. To address how the human brain dynamically computes these tradeoffs, we performed whole-brain fMRI while healthy young individuals engaged in a sequential gambling task. Participants were repeatedly confronted with the option to continue with throwing a die to accumulate monetary reward under escalating risk, or the alternative option to stop to bank the current balance. Within each gambling round, the accumulation of gains gradually increased reaction times for “continue” choices, indicating growing uncertainty in the decision to continue. Neural activity evoked by “continue” choices was associated with growing activity and connectivity of a cortico-subcortical “braking” network that positively scaled with the accumulated gains, including pre-supplementary motor area (pre-SMA), inferior frontal gyrus, caudate, and subthalamic nucleus (STN). The influence of the STN on continue-evoked activity in the pre-SMA was predicted by interindividual differences in risk-aversion attitudes expressed during the gambling task. Furthermore, activity in dorsal anterior cingulate cortex (ACC) reflected individual choice tendencies by showing increased activation when subjects made nondefault “continue” choices despite an increasing tendency to stop, but ACC activity did not change in proportion with subjective choice uncertainty. Together, the results implicate a key role of dorsal ACC, pre-SMA, inferior frontal gyrus, and STN in computing the trade-off between escalating reward and risk in sequential decision-making. SIGNIFICANCE STATEMENT Using a paradigm where subjects experienced increasing potential rewards coupled with increasing risk, this study addressed two unresolved questions in the field of decision-making: First, we investigated an “inhibitory” network of regions that has so far been investigated with externally cued action inhibition. In this study, we show that the dynamics in this network under increasingly risky decisions are predictive of subjects' risk attitudes. Second, we contribute to a currently ongoing debate about the anterior cingulate cortex's role in sequential foraging decisions by showing that its activity is related to making nondefault choices rather than to choice uncertainty
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